Intolerance of loud sounds in childhood: Is there an intergenerational association with grandmaternal smoking in pregnancy?

ABSTRACT: Recent research using the Avon Longitudinal Study of Parents and Children (ALSPAC) demonstrated an association between maternal grandmother smoking in pregnancy and the autistic traits of impaired social communication and repetitive behaviour in granddaughters but not grandsons, but of paternal grandmother smoking and early development of myopia in the grandchild. Here we investigate whether grandmaternal smoking in pregnancy is associated with intolerance to loud sounds. ALSPAC collected information during the index pregnancy from the study parents on the smoking habits, social and other features of their own parents. Maternal report when the child was aged 6 and 13 included hating loud sounds; at age 11 the child was tested for volume preference for listening to music through headphones.

SUBMITTER: Hall A 

PROVIDER: S-EPMC7039668 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature