Early Weight Loss and Treatment Response: Data From a Lifestyle Change Program in Clinical Practice.

ABSTRACT:

Introduction

The purpose of this study was to develop and validate a predictive model for the early identification of nonresponders to a 12-month lifestyle change program in clinical practice.

Methods

Investigators identified lifestyle change program participants in the electronic health records of a large healthcare delivery system between 2010 and 2017. Nonresponse was defined as weight gain or no weight loss at 12 months from the program initiation (baseline). Logistic regression with percentage weight change at 2-12 weeks from baseline was used as an independent predictor of nonresponse. Baseline demographics and clinical characteristics were also tested as potential predictors. The authors performed ten-fold cross-validation for model assessment and examined model perfo

SUBMITTER: Romanelli RJ 

PROVIDER: S-EPMC7039735 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature