Sex-Specific Differences in Circumpapillary Retinal Nerve Fiber Layer Thickness.

ABSTRACT:

Purpose

To investigate the role of sex on retinal nerve fiber layer (RNFL) thickness at 768 circumpapillary locations based on OCT findings.

Design

Population-based cross-sectional study.

Participants

We investigated 5646 eyes of 5646 healthy participants from the Leipzig Research Centre for Civilization Diseases (LIFE)-Adult Study of a predominantly white population.

Methods

All participants underwent standardized systemic assessments and ocular imaging. Circumpapillary RNFL (cRNFL) thickness was measured at 768 points equidistant from the optic nerve head using spectral-domain OCT (Spectralis; Heidelberg Engineering, Heidelberg, Germany). To control ocular magnification effects, the true scanning radius was estimated by scanning focus. Student t test was used

SUBMITTER: Li D 

PROVIDER: S-EPMC7039768 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature