Preserved cortical thickness, surface area and volume in adolescents with PTSD after childhood sexual abuse.

ABSTRACT: Exposure to childhood adverse events is associated with severe consequences for general health and structural and functional changes in the brain of its survivors. In order to unravel and in the end influence the pathway linking adversity and pathology, neuroimaging research is crucial. Up till now studies in minors are scarce and differ in type of adversity or methodology. Almost all studies report lower cortical thickness, but in a broad variety of regions. In this study we investigated cortical thickness measures and clinical data in a well circumscribed group of adolescents with PTSD related to childhood sexual abuse (CSA) (N = 21) and a healthy non-traumatised control group (N = 21). The ventromedial PFC (vmPFC), ACC, insula, and middle/superior temporal gyrus were chosen as ROI's due

SUBMITTER: Rinne-Albers MA 

PROVIDER: S-EPMC7039962 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature