Hematuria in aging men with hemophilia: Association with factor prophylaxis.

ABSTRACT:

Introduction

Macroscopic hematuria is considered a significant risk factor for urologic disease, and it is highly prevalent in people with hemophilia.

Aim

To determine whether prophylactic factor replacement therapy is associated with reduced occurrence of macroscopic hematuria in people with hemophilia in a post hoc analysis using data from a cross-sectional study conducted by the Age-Related Developments and Comobordities in Hemophilia (ADVANCE) Working Group that included males with hemophilia ≥40 years of age.

Methods

Data from 16 contributing centers, in 13 European countries and Israel, were analyzed using logistic regression. Of 532 recruited individuals, this analysis included 370 patients with moderate or severe hemophilia who received on-demand or prophylact

SUBMITTER: Qvigstad C 

PROVIDER: S-EPMC7040553 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature