Antibiotic Practice Patterns for Extremity Wound Infections among Blast-Injured Subjects.

ABSTRACT:

Introduction

We examined antibiotic management of combat-related extremity wound infections (CEWI) among wounded U.S. military personnel (2009-2012).

Methods

Patients were included if they sustained blast injuries, resulting in ≥1 open extremity wound, were admitted to participating U.S. hospitals, developed a CEWI (osteomyelitis or deep soft-tissue infections) within 30 days post-injury, and received ≥3 days of relevant antibiotic (s) for treatment.

Results

Among 267 patients, 133 (50%) had only a CEWI, while 134 (50%) had a CEWI plus concomitant non-extremity infection. In the pre-diagnosis period (4-10 days prior to CEWI diagnosis), 95 (36%) patients started a new antibiotic with 28% of patients receiving ≥2 antibiotics. During CEWI diagnosis week (±3 days of diagn

SUBMITTER: Stewart L 

PROVIDER: S-EPMC7041850 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature