A case report of heart transplant for ischaemic cardiomyopathy from lupus coronary vasculitis.

ABSTRACT:

Background

Coronary vasculitis is a rare, life-threatening complication of systemic lupus erythematosus (SLE).

Case summary

A 23-year-old woman with SLE presented with typical angina and worsening dyspnoea on exertion. Coronary angiography revealed severe triple vessel disease with a 'string of beads' appearance classic for coronary vasculitis. Transthoracic echocardiogram revealed ejection fraction of 25-30% with a severely hypokinetic distal septum and distal anterior wall and an akinetic apical wall. Despite vasculitis treatment with cyclophosphamide and pulse-dose steroids, her coronary vasculitis did not improve. She was refractory to anti-anginal and guideline-directed medical therapy for heart failure and successfully underwent orthotopic heart transplant (OHT).

Di

SUBMITTER: Nandkeolyar S 

PROVIDER: S-EPMC7042145 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature