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A case report: metastasis of melanoma to the heart in an era of immunotherapy.


ABSTRACT:

Background

Cardiac metastasis of melanoma rarely causes heart failure symptoms and the recognition of cardiac involvement is in most cases first established post-mortem. Surgical removal might be considered in selected cases in patients with an inflow or outflow tract obstruction even though the survival remains poor. Frequently, the metastasis cannot be removed and therapeutic options include conventional chemotherapy or immunotherapy, which is currently recommended as first-line treatment. Since the introduction of immunotherapy survival in metastatic disease has significantly increased but data on patients treated for melanoma with cardiac involvement are scarce.

Case summary

A 65-year-old man presented with dyspnoea and fatigue. Computed tomography scan revealed tumour p

SUBMITTER: Poulsen CB 

PROVIDER: S-EPMC7042148 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature