An audit of retinal lymphoma treatment at the University of California San Francisco.

ABSTRACT:

Background/objectives

To evaluate retinal lymphoma treatment at the University of California San Francisco.

Subjects/methods

Prospective observational audit. Patients were treated systemically, usually with: methotrexate, temozolomide, and rituximab induction; etoposide consolidation; and maintenance with lenalidomide or another immunomodulatory agent. Persistent disease was treated initially by ocular radiotherapy or intravitreal melphalan and latterly by vitrectomy.

Results

The cohort comprised eight females and two males. The median age was 58 years (range, 38-73). Ocular manifestations were initially unilateral in four patients. Vitreous and subretinal infiltrates were initially present in 16 and 12 eyes, respectively, with three eyes having vision of 20/200 or wo

SUBMITTER: Damato B 

PROVIDER: S-EPMC7042248 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature