Systematic review and meta-analysis of transoral laser microsurgery in hypopharyngeal carcinoma.

ABSTRACT:

Background

Transoral laser microsurgery has been suggested as an alternative treatment modality for hypopharyngeal carcinoma. The purpose of this study is to systematically review the oncologic and functional outcomes of patients with hypopharyngeal carcinoma when treated with primary transoral laser microsurgery.

Methods

A comprehensive literature search was performed using PRISMA methodology on OVID MEDLINE and EMBASE. Meta-analysis was completed for oncological outcomes.

Results

Six studies reported quality of life outcomes five reported oncologic outcomes. A median of 95% (range 0.83-0.98) patients achieving gastrostomy independence, a median of 3% (range 0%-6%) were tracheostomy dependent, and a median of 97% (Range 0.89-1.0) were able to preserve their larynx. P

SUBMITTER: Lane C 

PROVIDER: S-EPMC7042655 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature