Association of Germline Genetic Testing Results With Locoregional and Systemic Therapy in Patients With Breast Cancer.

ABSTRACT:

Importance

The increasing use of germline genetic testing may have unintended consequences on treatment. Little is known about how women with pathogenic variants in cancer susceptibility genes are treated for breast cancer.

Objective

To determine the association of germline genetic testing results with locoregional and systemic therapy use in women diagnosed with breast cancer.

Design, setting, and participants

For this population-based cohort study, data from women aged 20 years or older who were diagnosed with stages 0 to III breast cancer between 2014 and 2016 were accrued from the Surveillance, Epidemiology and End Results (SEER) registries of Georgia and California. The women underwent genetic testing within 3 months after diagnosis and were reported to the Georg

SUBMITTER: Kurian AW 

PROVIDER: S-EPMC7042883 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature