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When to vaccinate a fluctuating wildlife population: Is timing everything?


ABSTRACT: Wildlife vaccination is an important tool for managing the burden of infectious disease in human populations, domesticated livestock and various iconic wildlife. Although substantial progress has been made in the field of vaccine designs for wildlife, there is a gap in our understanding of how to time wildlife vaccination, relative to host demography, to best protect a population.We use a mathematical model and computer simulations to assess the outcomes of vaccination campaigns that deploy vaccines once per annual population cycle.Optimal timing of vaccination is an important consideration in animals with short to intermediate life spans and a short birthing season. Vaccines that are deployed shortly after the birthing season best protect the host population.The importance of timing is gr

SUBMITTER: Schreiner CL 

PROVIDER: S-EPMC7043377 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature