Dual Predation by Bacteriophage and <i>Bdellovibrio bacteriovorus</i> Can Eradicate <i>Escherichia coli</i> Prey in Situations where Single Predation Cannot.

ABSTRACT: Bacteria are preyed upon by diverse microbial predators, including bacteriophage and predatory bacteria, such as Bdellovibrio bacteriovorus While bacteriophage are used as antimicrobial therapies in Eastern Europe and are being applied for compassionate use in the United States, predatory bacteria are only just beginning to reveal their potential therapeutic uses. However, predation by either predator type can falter due to different adaptations arising in the prey bacteria. When testing poultry farm wastewater for novel Bdellovibrio isolates on Escherichia coli prey lawns, individual composite plaques were isolated containing both an RTP (rosette-tailed-phage)-like-phage and a B. bacteriovorus strain and showing central prey lysis and halos of extra lysis. Comb

SUBMITTER: Hobley L 

PROVIDER: S-EPMC7043672 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature