Do Baseline Asthma and Allergic Sensitization Characteristics Predict Responsiveness to Mouse Allergen Reduction?

ABSTRACT:

Background

Mouse allergen reduction is associated with improvements in asthma among sensitized and exposed children, but whether clinical characteristics predict responsiveness to allergen reduction is unclear.

Objective

To examine the effects of clinical characteristics on relationships between mouse allergen reduction and asthma outcomes.

Methods

We performed a secondary analysis of data from a randomized clinical trial of a mouse allergen intervention, examining the effects of atopy, demographic characteristics, lung function, asthma control, and asthma severity on relationships between mouse allergen reduction and asthma outcomes.

Results

Participants were predominantly low-income and minority (78% black, 22% Hispanic), and had persistent asthma. Among less

SUBMITTER: Ahmed A 

PROVIDER: S-EPMC7043786 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature