Real-time 3T MRI-guided cardiovascular catheterization in a porcine model using a glass-fiber epoxy-based guidewire.

ABSTRACT: PURPOSE:Real-time magnetic resonance imaging (MRI) is a promising alternative to X-ray fluoroscopy for guiding cardiovascular catheterization procedures. Major challenges, however, include the lack of guidewires that are compatible with the MRI environment, not susceptible to radiofrequency-induced heating, and reliably visualized. Preclinical evaluation of new guidewire designs has been conducted at 1.5T. Here we further evaluate the safety (device heating), device visualization, and procedural feasibility of 3T MRI-guided cardiovascular catheterization using a novel MRI-visible glass-fiber epoxy-based guidewire in phantoms and porcine models. METHODS:To evaluate device safety, guidewire tip heating (GTH) was measured in phantom experiments with different combinations of catheters and gui

SUBMITTER: Li X 

PROVIDER: S-EPMC7043930 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature