Predicted Drosophila Interactome Resource and web tool for functional interpretation of differentially expressed genes.

ABSTRACT: Drosophila melanogaster is a well-established model organism that is widely used in genetic studies. This species enjoys the availability of a wide range of research tools, well-annotated reference databases and highly similar gene circuitry to other insects. To facilitate molecular mechanism studies in Drosophila, we present the Predicted Drosophila Interactome Resource (PDIR), a database of high-quality predicted functional gene interactions. These interactions were inferred from evidence in 10 public databases providing information for functional gene interactions from diverse perspectives. The current version of PDIR includes 102 835 putative functional associations with balanced sensitivity and specificity, which are expected to cover 22.56% of all Drosophila protein interactions. Thi

SUBMITTER: Ding XB 

PROVIDER: S-EPMC7044104 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature