Association between vitamin D and fatigue in patients with rheumatoid arthritis: a cross-sectional study.

ABSTRACT:

Objectives

In rheumatoid arthritis (RA), fatigue is an important complaint with a significant impact on quality of life. Vitamin D has modulatory effects on cells of the immune system and may potentially affect RA disease activity and thereby RA-related fatigue. The purpose of this study was to explore associations between fatigue and vitamin D status in patients with RA.

Design

Hypothesis-generating cross-sectional study.

Setting

Scheduled follow-up visits at a hospital-based general rheumatology clinic.

Participants

Patients (n=169) with established RA.

Primary outcome measures and anlyses

Fatigue, assessed by the Chalder fatigue questionnaire, and serum concentrations of 25-hydroxyvitamin D (25(OH)D), assessed by liquid chromatography-tandem mass spec

SUBMITTER: Jelsness-Jorgensen LP 

PROVIDER: S-EPMC7044854 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature