Vitamin D supplementation to improve pregnancy and perinatal outcomes: an overview of 42 systematic reviews.

ABSTRACT:

Objective

To review the evidence to assess effectiveness of vitamin D supplementation during pregnancy and associations of serum vitamin D levels with perinatal outcomes.

Design

Overview of systematic reviews (SRs).

Data sources

Searches conducted in January 2019: Ovid Medline (1946-), Cochrane Library databases.

Eligibility criteria for selecting studies

Two reviewers independently screened titles and abstracts, and full texts using predefined inclusion criteria: SRs evaluating vitamin D supplementation in pregnant women and/or examining the association between serum vitamin D levels reporting at least one predefined perinatal outcome. Only SRs with high AMSTAR scores were analysed.

Data extraction and synthesis

Data were extracted independently by one

SUBMITTER: Bialy L 

PROVIDER: S-EPMC7044866 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature