Does intensive glycaemic control promote healing in diabetic foot ulcers? - a feasibility study.

ABSTRACT:

Introduction

One in four diabetes patients will develop a foot ulcer over their lifetime. The role of glycaemic control in the healing of foot ulcers in diabetes patients is not supported by randomised controlled trial (RCT) data.

Objectives

To determine the feasibility of an RCT of glycaemic control with intensive insulin therapy in diabetic foot ulcer, by assessing: entry criteria, fasting capillary blood glucose (FCBG) medication satisfaction and sensitivity of different ulcer-healing endpoints to glycaemic control.

Design

Two substudies: one cross-sectional and one single-arm prospective.

Setting

Single-centre secondary care diabetic foot clinic in New Zealand.

Participants

Substudy 1: 78 participants consisting of all people ≥18 years with a diabeti

SUBMITTER: Dissanayake A 

PROVIDER: S-EPMC7044945 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature