Guideline-directed medical therapy in elderly patients with heart failure with reduced ejection fraction: a cohort study.

ABSTRACT:

Objectives and design

Guideline-directed medical therapy (GDMT) with renin-angiotensin system (RAS) inhibitors and beta-blockers has improved survival in patients with heart failure with reduced ejection fraction (HFrEF). As clinical trials usually do not include very old patients, it is unknown whether the results from clinical trials are applicable to elderly patients with HF. This study was performed to investigate the clinical characteristics and treatment strategies for elderly patients with HFrEF in a large prospective cohort.

Setting

The Korean Acute Heart Failure (KorAHF) registry consecutively enrolled 5625 patients hospitalised for acute HF from 10 tertiary university hospitals in Korea.

Participants

In this study, 2045 patients with HFrEF who were aged 65 y

SUBMITTER: Seo WW 

PROVIDER: S-EPMC7044987 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature