Tuberculosis among patients treated with TNF inhibitors for rheumatoid arthritis, ankylosing spondylitis and psoriatic arthritis in Slovenia: a cohort study.

ABSTRACT:

Objectives

This study aimed to assess the risk of tuberculosis (TB) in patients with rheumatoid arthritis (RA), ankylosing spondylitis (AS) and psoriatic arthritis (PsA) treated with any of the commercially available tumour necrosis factor inhibitors (TNFis) in Slovenia.

Design

This is a cohort, registry (biorx.si) cross-linked with the Slovenian National TB Registry.

Setting

National, involving all Slovenian rheumatology centres (six secondary and two secondary/tertiary).

Participants

2429 patients with RA, AS or PsA exposed to at least one TNFi participated in the study.

Primary and secondary outcome measures

The primary outcome measures were age-adjusted and sex-adjusted TB incidence rates (IRs) and the standardised incidence ratios (SIRs) compared wi

SUBMITTER: Rotar Z 

PROVIDER: S-EPMC7045120 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature