Economic evaluation of the OSAC randomised controlled trial: oral corticosteroids for non-asthmatic adults with acute lower respiratory tract infection in primary care.

ABSTRACT:

Objective

To estimate the costs and outcomes associated with treating non-asthmatic adults (nor suffering from other lung-disease) presenting to primary care with acute lower respiratory tract infection (ALRTI) with oral corticosteroids compared with placebo.

Design

Cost-consequence analysis alongside a randomised controlled trial. Perspectives included the healthcare provider, patients and productivity losses associated with time off work.

Setting

Fifty-four National Health Service (NHS) general practices in England.

Participants

398 adults attending NHS primary practices with ALRTI but no asthma or other chronic lung disease, followed up for 28 days.

Interventions

2× 20 mg oral prednisolone per day for 5 days versus matching placebo tablets.

Outcome

SUBMITTER: Moure-Fernandez A 

PROVIDER: S-EPMC7045138 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature