Challenges for funders in monitoring compliance with policies on clinical trials registration and reporting: analysis of funding and registry data in the UK.

ABSTRACT:

Objectives

To evaluate compliance by researchers with funder requirements on clinical trial transparency, including identifying key areas for improvement; to assess the completeness, accuracy and suitability for annual compliance monitoring of the data routinely collected by a research funding body.

Design

Descriptive analysis of clinical trials funded between February 2011 and January 2017 against funder policy requirements.

Setting

Public medical research funding body in the UK.

Data sources

Relevant clinical trials were identified from grant application details, post-award grant monitoring systems and the International Standard Randomised Controlled Trial Number (ISRCTN) registry.

Main outcome measure

The proportion of all Medical Research Council (MR

SUBMITTER: Knowles RL 

PROVIDER: S-EPMC7045207 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature