Association of trajectory of body mass index with knee pain risk in Japanese middle-aged women in a prospective cohort study: the Japan Nurses' Health Study.

ABSTRACT:

Objectives

To investigate whether body mass index (BMI) trajectory, lifestyle and reproductive factors are associated with knee pain risk among middle-aged women.

Design

Prospective study of the Japan Nurses' Health Study (JNHS).

Setting

The JNHS investigates the health of female nurses in Japan. Biennial follow-up questionnaires are mailed to the participants.

Participants

The 7434 women aged over 40 years who responded to the 10-year self-administered follow-up questionnaire.

Primary outcome measure

Self-reported knee pain at the 10-year follow-up was the primary outcome. We analysed BMI (normal or overweight) trajectory data from a baseline survey to the 10-year follow-up survey using group-based trajectory modelling. Exposure measurements were BMI tr

SUBMITTER: Ito A 

PROVIDER: S-EPMC7045261 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature