Thrombolysis related symptomatic intracranial hemorrhage in estimated versus measured body weight.

ABSTRACT:

Background and aim

In acute ischemic stroke, under- or overestimation of body weight can lead to dosing errors of recombinant tissue plasminogen activator with consequent reduced efficacy or increased risk of hemorrhagic complications. Measurement of body weight is more accurate than estimation of body weight but potentially leads to longer door-to-needle times. Our aim was to assess if weight modality (estimation of body weight versus measurement of body weight) is associated with (i) symptomatic intracranial hemorrhage rate, (ii) clinical outcome, and (iii) door-to-needle times.

Methods

Consecutive patients treated with intravenous thrombolysis between 2009 and 2016 from 14 hospitals were included. Baseline characteristics and outcome parameters were retrieved from medical

SUBMITTER: Truc My Nguyen T 

PROVIDER: S-EPMC7045279 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature