Association of pulse rate with outcomes in heart failure with reduced ejection fraction: a retrospective cohort study.

ABSTRACT:

Background

In a real-world setting, the effect of pulse rate measured at the time of diagnosis and serially during follow-up and management, on outcomes in heart failure with reduced ejection fraction (HFrEF), has not been well-studied. Furthermore, how beta-blockade use in a real-world situation modifies this relation between pulse rate and outcomes in HFrEF is not well-known. Hence, we identified a large, national, real-world cohort of HFrEF to examine the association of pulse rate and outcomes.

Methods

Using Veterans Affairs (VA) national electronic health records we identified incident HFrEF cases between 2006 and 2012. We examined the associations of both baseline and serially measured pulse rates, with mortality and days hospitalized per year for heart failure and for

SUBMITTER: Kurgansky KE 

PROVIDER: S-EPMC7045436 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature