Amine-Functionalized ZIF-8 as a Fluorescent Probe for Breath Volatile Organic Compound Biomarker Detection of Lung Cancer Patients.

ABSTRACT: The highly thermally and chemically stable imidazole framework ZIF-8 samples were separately postmodified with amine groups by using N,N'-dimethylethylenediamine (MMEN) and N,N-dimethylaminoethylamine (MAEA), which had the same molecular formula but different structures. The modified ZIF-8 samples (ZIF-8@amine) were thoroughly characterized, including powder X-ray diffractometry, Fourier-transformed infrared spectroscopy, and physical adsorption at 77 K by nitrogen, thermogravimetric analysis, and photophysical characterization. Results showed that after modification, the Brunauer-Emmett-Teller surface area and total pore volume both increased, almost one time higher than those of the original ZIF-8 sample, and followed the order: ZIF-8-MMEN > ZIF-8-MAEA > ZIF-8. Furthermore, the N-H group

SUBMITTER: Xia Y 

PROVIDER: S-EPMC7045493 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature