A scoping review of core outcome sets and their 'mapping' onto real-world data using prostate cancer as a case study.

ABSTRACT:

Background

A Core Outcomes Set (COS) is an agreed minimum set of outcomes that should be reported in all clinical studies related to a specific condition. Using prostate cancer as a case study, we identified, summarized, and critically appraised published COS development studies and assessed the degree of overlap between them and selected real-world data (RWD) sources.

Methods

We conducted a scoping review of the Core Outcome Measures in Effectiveness Trials (COMET) Initiative database to identify all COS studies developed for prostate cancer. Several characteristics (i.e., study type, methods for consensus, type of participants, outcomes included in COS and corresponding measurement instruments, timing, and sources) were extracted from the studies; outcomes were classified

SUBMITTER: Meregaglia M 

PROVIDER: S-EPMC7045588 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature