Chemoenzymatic Halocyclization of 4-Pentenoic Acid at Preparative Scale.

ABSTRACT: The scale-up of chemoenzymatic bromolactonization to 100 g scale is presented, together with an identification of current limitations. The preparative-scale reaction also allowed for meaningful mass balances identifying current bottlenecks of the chemoenzymatic reaction.

SUBMITTER: Hofler GT 

PROVIDER: S-EPMC7045808 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature