Metagenomics of Imported Multidrug-Resistant Mycobacterium leprae, Saudi Arabia, 2017.

ABSTRACT: Using shotgun metagenomics, we identified an imported case of multidrug-resistant Mycobacterium leprae in a Filipino resident of Saudi Arabia in 2017. We determined the phylogenomic lineage (3K1) and identified mutations in rpoB and rrs corresponding to the multidrug-resistance phenotype clinically observed. Metagenomics sequencing can be used to identify multidrug-resistant M. leprae.

SUBMITTER: Guan Q 

PROVIDER: S-EPMC7045828 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature