Thirty-Year Risk of Cardiovascular Disease Events in Adolescents with Severe Obesity.

ABSTRACT:

Objective

Quantifying risk for cardiovascular disease (CVD) events among adolescents is difficult owing to the long latent period between risk factor development and disease outcomes. This study examined the 30-year CVD event risk among adolescents with severe obesity treated with and without metabolic and bariatric surgery (MBS), compared with youths with moderate obesity, overweight, or normal weight.

Methods

Cross-sectional and longitudinal comparisons of five frequency-matched (age and diabetes status) groups were performed: normal weight (n = 247), overweight (n = 54), obesity (n = 131), severe obesity without MBS (n = 302), and severe obesity undergoing MBS (n = 215). A 30-year CVD event score developed by the Framingham Heart Study was the primary outcome. Data are me

SUBMITTER: Ryder JR 

PROVIDER: S-EPMC7045971 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature