A multi-omics dataset of heat-shock response in the yeast RNA binding protein Mip6.

ABSTRACT: Gene expression is a biological process regulated at different molecular levels, including chromatin accessibility, transcription, and RNA maturation and transport. In addition, these regulatory mechanisms have strong links with cellular metabolism. Here we present a multi-omics dataset that captures different aspects of this multi-layered process in yeast. We obtained RNA-seq, metabolomics, and H4K12ac ChIP-seq data for wild-type and mip6Δ strains during a heat-shock time course. Mip6 is an RNA-binding protein that contributes to RNA export during environmental stress and is informative of the contribution of post-transcriptional regulation to control cellular adaptations to environmental changes. The experiment was performed in quadruplicate, and the different omics measurements were obt

SUBMITTER: Nuno-Cabanes C 

PROVIDER: S-EPMC7046740 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature