Fatigue numeric rating scale validity, discrimination and responder definition in patients with psoriatic arthritis.

ABSTRACT:

Objectives

This study assessed the psychometric properties of the fatigue numeric rating scale (NRS) and sought to establish values for clinically meaningful change (responder definition).

Methods

Using disease-specific clinician-reported and patient-reported data from two randomised clinical trials of patients with psoriatic arthritis (PsA), the fatigue NRS was evaluated for test-retest reliability, construct validity and responsiveness. A responder definition was also explored using anchor-based and distribution-based methods.

Results

Test-retest reliability analyses supported the reproducibility of the fatigue NRS in patients with PsA (intraclass correlation coefficient=0.829). Mean (SD) values at baseline and week 2 were 5.7 (2.2) and 5.7 (2.4), respectively. Supp

SUBMITTER: Gladman D 

PROVIDER: S-EPMC7046948 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature