Multi-pathway multi-echo acquisition and neural contrast translation to generate a variety of quantitative and qualitative image contrasts.

ABSTRACT:

Purpose

Clinical exams typically involve acquiring many different image contrasts to help discriminate healthy from diseased states. Ideally, 3D quantitative maps of all of the main MR parameters would be obtained for improved tissue characterization. Using data from a 7-min whole-brain multi-pathway multi-echo (MPME) scan, we aimed to synthesize several 3D quantitative maps (T₁ and T₂ ) and qualitative contrasts (MPRAGE, FLAIR, T₁ -weighted, T₂ -weighted, and proton density [PD]-weighted). The ability of MPME acquisitions to capture large amounts of information in a relatively short amount of time suggests it may help reduce the duration of neuro MR exams.

Methods

Eight healthy volunteers were imaged at 3.0T using a 3D isotropic (

SUBMITTER: Cheng CC 

PROVIDER: S-EPMC7047605 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature