Validation of the global lung initiative 2012 multi-ethnic spirometric reference equations in healthy urban Zimbabwean 7-13 year-old school children: a cross-sectional observational study.

ABSTRACT:

Background

The 2012 Global Lung Function Initiative (GLI₂₀₁₂) provide multi-ethnic spirometric reference equations (SRE) for the 3-95 year-old age range, but Sub-Saharan African populations are not represented. This study aimed to evaluate the fit of the African-American GLI₂₀₁₂ SRE to a population of healthy urban and peri-urban Zimbabwean school-going children (7-13 years).

Methods

Spirometry and anthropometry were performed on black-Zimbabwean children recruited from three primary schools in urban and peri-urban Harare, with informed consent and assent. Individuals with a history or current symptoms of respiratory disease or with a body mass index-z score (BMI) < - 2 were excluded. Spirometry z-scores were generated from African-American GLI₂₀₁₂

SUBMITTER: Madanhire T 

PROVIDER: S-EPMC7048020 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature