Tissue Doppler Imaging for anthracycline cardiotoxicity monitoring in pediatric patients with cancer.

ABSTRACT:

Background

Cardiotoxic effects of anthracycline therapy are a major cause of morbidity for childhood cancer survivors. The aim of this retrospective evaluation is to assess the efficacy of Tissue Doppler Imaging in the early detection of myocardial alterations in these patients.

Methods

A population of 50 childhood cancer survivors (32 males and 18 females) who have been treated with anthracyclines was evaluated by standard and TDI echocardiographic examination of the basal and median region of the interventricular septum (IVSb, IVSm), of the left ventricular posterior wall (LVPWb, LVPWm), and of the mitral annulus; the results were compared with those obtained from a population of 50 healthy age-matched and sex-matched controls by using the Student test. The clinical and ec

SUBMITTER: Venturelli F 

PROVIDER: S-EPMC7048119 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature