Evaluating Mechanisms of Postoperative Delirium and Cognitive Dysfunction Following Elective Spine Surgery in Elderly Patients (CONFESS): Protocol for a Prospective Observational Trial.

ABSTRACT:

Background

Elderly people are at particular high risk for postoperative delirium (POD) following spine surgery, which is associated with longer hospital stays, higher costs, risk for delayed complications, long-term care dependency, and cognitive dysfunction (POCD). It is insufficiently understood which mechanisms and risk factors contribute to the development of POD and POCD following these major but plannable surgeries.

Objective

This study aims to identify modifiable risk factors in spine surgery. A better understanding thereof would help adapt medical management and surgical strategies to individual risk profiles.

Methods

This is a single-center observational study jointly conducted by the departments of neurosurgery, neurology, and anesthesiology at a tertiary ca

SUBMITTER: Muller J 

PROVIDER: S-EPMC7048391 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature