Modelling impact and cost-effectiveness of oral pre-exposure prophylaxis in 13 low-resource countries.

ABSTRACT:

Introduction

Oral pre-exposure prophylaxis (PrEP) provision is a priority intervention for high HIV prevalence settings and populations at substantial risk of HIV acquisition. This mathematical modelling analysis estimated the impact, cost and cost-effectiveness of scaling up oral PrEP in 13 countries.

Methods

We projected the impact and cost-effectiveness of oral PrEP between 2018 and 2030 using a combination of the Incidence Patterns Model and the Goals model. We created four PrEP rollout scenarios involving three priority populations-female sex workers (FSWs), serodiscordant couples (SDCs) and adolescent girls and young women (AGYW)-both with and without geographic prioritization. We applied the model to 13 countries (Eswatini, Ethiopia, Haiti, Kenya, Lesotho, Mozambique,

SUBMITTER: Pretorius C 

PROVIDER: S-EPMC7048876 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature