Corticostriatal Circuits Encode the Subjective Value of Perceived Control.

ABSTRACT: The ability to perceive and exercise control over an outcome is both desirable and beneficial to our well-being. It has been shown that animals and humans alike exhibit behavioral bias towards seeking control and that such bias recruits the ventromedial prefrontal cortex (vmPFC) and striatum. Yet, this bias remains to be quantitatively captured and studied neurally. Here, we employed a behavioral task to measure the preference for control and characterize its neural underpinnings. Participants made a series of binary choices between having control and no-control over a game for monetary reward. The mere presence of the control option evoked activity in the ventral striatum. Importantly, we manipulated the expected value (EV) of each choice pair to extract the pairing where participants wer

SUBMITTER: Wang KS 

PROVIDER: S-EPMC7049308 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature