Ontology highlight
ABSTRACT:
SUBMITTER: Cardoso VM
PROVIDER: S-EPMC7049567 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
Biotechnology reports (Amsterdam, Netherlands) 20200222
The impact of cultivation strategy on the cost of recombinant protein production is crucial for defining cost-effective bioreactor operation conditions. This paper presents a methodology to estimate and compare cost impacts related to utilities as well as medium composition, using simple design equations and accessible data. Data from batch bioreactor cultures were used as case study involving the production of pneumococcal surface protein A, a soluble recombinant protein, employing <i>E. coli</ ...[more]