Timeliness of signal detection for adverse events following influenza vaccination in young children: a simulation case study.

ABSTRACT:

Objectives

To determine how soon after commencement of the seasonal influenza vaccination programme, the AusVaxSafety active vaccine safety surveillance system, currently in use across Australia, would have detected a safety signal had it been operating in 2010 when there was an unprecedented number of febrile seizures in young children associated with one specific influenza vaccine brand, Fluvax (CSL Biotherapies).

Design

Simulation study.

Setting

Western Australian vaccine influenza coverage and adverse event surveillance data.

Outcome measures

Simulated solicited responses from caregivers who would have received an SMS survey about adverse events experienced following seasonal influenza vaccination of their children aged 6 months to <5 years.

Participants

SUBMITTER: Jacoby P 

PROVIDER: S-EPMC7050305 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature