Effect of long-term feeding of the Obudu natural honey and table sugar-sweetened diets on obesity and pro-inflammatory biomarkers in rats.

ABSTRACT:

Background

This study investigated long-term effect of the Obudu honey on selected biomarkers of energy storage regulation, compared to table sugar.

Methods

Fifty Wistar rats assigned to 5 groups of 10 rats each, were fed rat chow only (NC), 8% table sugar (S8%), 16% table sugar (S16%), 10% honey (H10%) and 20% honey (H20%) diets respectively, for 29 weeks. On dry weight basis, the percentages of table sugar and honey for each level of incorporation were equivalent. Diet intake, body weights and fasting blood glucose (FBG) were measured fortnightly. At the end of the study, serum glucose, insulin, leptin and tissue necrosis factor - α (TNF-α), wet weight of white adipose tissues (WAT) were measured.

Results

After an initial adjustment to the diets, there was no signif

SUBMITTER: Atangwho IJ 

PROVIDER: S-EPMC7050836 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature