Design and implementation of a cross-sectional nutritional phenotyping study in healthy US adults.

ABSTRACT:

Background

Metabolic imbalance is a key determinant of risk of chronic diseases. Metabolic health cannot be assessed solely by body mass calculations or by static, fasted state biochemical readouts. Although previous studies have described temporal responses to dietary challenges, these studies fail to assess the environmental factors associated with certain metabolic phenotypes and therefore, provide little scientific rationale for potentially effective intervention strategies.

Methods/design

In this phenotyping study of healthy US adults, we are evaluating lifestyle, biological and environmental factors in addition to metabolic parameters to determine the factors associated with variations in metabolic health. A series of practical fitness, dietary, and emotional challenge

SUBMITTER: Baldiviez LM 

PROVIDER: S-EPMC7050916 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature