Identification of Toxicity Effects of Cu₂O Materials on C. elegans as a Function of Environmental Ionic Composition.

ABSTRACT: Previous work has shown that spherical CuO nanomaterials show negative effects on cell and animal physiology. The biological effects of Cu₂O materials, which posess unique chemical features compared to CuO nanomaterials and can be synthesized in a similarly large variety of shapes and sizes, are comparatively less studied. Here, we synthesized truncated octahedral Cu₂O particles and characterized their structure, stability, and physiological effects in the nematode worm animal model, Caenorhabditis elegans. Cu₂O particles were found to be generally stable in aqueous media, although the particles did show signs of oxidation and leaching of Cu²⁺ within hours in worm growth media. The particles were found to be especially sensitive to inorgan

SUBMITTER: Munro CJ 

PROVIDER: S-EPMC7051015 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature