Ontology highlight
ABSTRACT:
SUBMITTER: Patel H
PROVIDER: S-EPMC7051137 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Patel Harsita H Dunican Claire C Cunnington Aubrey J AJ
Virulence 20201201 1
<i>Plasmodium falciparum</i> malaria is classified as either uncomplicated or severe, determining clinical management and providing a framework for understanding pathogenesis. Severe malaria in children is defined by the presence of one or more features associated with adverse outcome, but there is wide variation in the predictive value of these features. Here we review the evidence for the usefulness of these features, alone and in combination, to predict death and other adverse outcomes, and w ...[more]