Association of Ultraviolet Radiation Exposure With Dermatomyositis in a National Myositis Patient Registry.

ABSTRACT:

Objective

Dermatomyositis (DM) has been associated with geospatial differences in ultraviolet (UV) radiation, but the role of individual determinants of UV exposure prior to diagnosis is unknown. The objective was to examine the role of those individual determinants.

Methods

We analyzed questionnaire data from 1,350 adults in a US national myositis registry (638 with DM, 422 with polymyositis [PM], and 290 with inclusion body myositis [IBM] diagnosed at ages 18-65 years), examining the likelihood of DM compared with PM and IBM diagnosis, in relation to self-reported sunburn history and job- and hobby-related sun exposures in the year prior to diagnosis. We estimated odds ratios (ORs) and 95% confidence intervals (95% CIs) using logistic regression adjusted for age, skin tone

SUBMITTER: Parks CG 

PROVIDER: S-EPMC7051886 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature