Novel gastrointestinal disease in common marmosets characterised by duodenal dilation: a clinical and pathological study.

ABSTRACT: Common marmosets (Callithrix jacchus) are frequently used for biomedical research but gastrointestinal diseases have been major health problems to maintain captive marmosets. We have diagnosed a novel gastrointestinal disease in marmosets, as which we propose to call 'marmoset duodenal dilation syndrome'; this disease is characterised by proximal duodenal obstruction and dilation. This study aimed to reveal the clinical and pathological findings of this syndrome and establish appropriate diagnostic imaging methods. Animals with the syndrome comprised 21.9% of the necropsy cases at the Central Institute for Experimental Animals in Kawasaki, Japan. The syndrome is characterised by clinical signs included vomiting, bloating, and weight loss. Grossly, all diseased animals exhibited significant

SUBMITTER: Mineshige T 

PROVIDER: S-EPMC7052236 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature