Comparison of ¹⁸F-sodium fluoride PET/CT, ¹⁸F-fluorocholine PET/CT and diffusion-weighted MRI for the detection of bone metastases in recurrent prostate cancer: a cost-effectiveness analysis in France.

ABSTRACT:

Background

The diagnostic performance of ¹⁸F-sodium fluoride positron emission tomography/computed tomography (PET/CT) (NaF), ¹⁸F-fluorocholine PET/CT (FCH) and diffusion-weighted whole-body magnetic resonance imaging (DW-MRI) in detecting bone metastases in prostate cancer (PCa) patients with first biochemical recurrence (BCR) has already been published, but their cost-effectiveness in this indication have never been compared.

Methods

We performed trial-based and model-based economic evaluations. In the trial, PCa patients with first BCR after previous definitive treatment were prospectively included. Imaging readings were performed both on-site by local specialists and centrally by experts. The economic evaluation extrapolated the diagnostic performan

SUBMITTER: Gauthe M 

PROVIDER: S-EPMC7052960 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature