Assessment of Acute Serum Iron, Non-Transferrin-Bound Iron, and Gastrointestinal Symptoms with 3-Week Consumption of Iron-Enriched Aspergillus oryzae Compared with Ferrous Sulfate.

ABSTRACT:

Background

Iron deficiency anemia (IDA) is a widespread nutritional deficiency, and iron supplementation, especially with ferrous sulfate (FeSO₄), is the most common strategy to treat IDA; however, compliance is often poor with daily FeSO₄ owing to negative side effects. In a previous study, iron from iron-enriched Aspergillus oryzae [Ultimine^® Koji Iron (ULT)] was absorbed similarly to FeSO₄.

Objectives

The main objective of this study was to assess the safety of consuming ULT in terms of increasing non-transferrin-bound iron (NTBI) and gastrointestinal distress.

Methods

Young female participants (n  = 16) with serum ferritin <40 μg/L were randomly assigned to a double-blind, 9-wk crossover study with a 3-wk p

SUBMITTER: Bries AE 

PROVIDER: S-EPMC7053575 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature