Physical activity and breast cancer risk: results from the UK Biobank prospective cohort.

ABSTRACT:

Background

Previous studies suggest a protective role of physical activity in breast cancer risk, largely based on self-reported activity. We aimed to clarify this association by examining breast cancer risk in relation to self-reported physical activity, informed by accelerometer-based measures in a large subset of participants.

Methods

We analysed data from 47,456 premenopausal and 126,704 postmenopausal women in UK Biobank followed from 2006 to 2014. Physical activity was self-reported at baseline, and at resurvey in a subsample of 6443 participants. Accelerometer data, measured from 2013 to 2015, were available in 20,785 women. Relative risks (RRs) and 95% confidence intervals (CIs) were calculated by using multivariable-adjusted Cox regression.

Results

A total of

SUBMITTER: Guo W 

PROVIDER: S-EPMC7054300 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature